Shaquille O'Neal and Charles Barkley have never shied away from taking brutal shots at each other on and that continued Saturday with a ruthless line by Shaq that left NBA fans in tears of laughter.

Barkley made the interesting decision to not wear a tie with his suit. Ernie Johnson pointed that out while coming back from a break, calling Barkley, "Slappy."

"Didn’t want to take away from my face," Barkley said.

Ernie Johnson quickly fired back with a funny line: "OK good, that’s not happening."

And then Shaq came from the top rope with this five-word message: "Shut your ugly ass up."

Fans loved it: